Figure 4

Principal component analysis (PCA) plots factored on hearing groups 1 (normal hearing to mild hearing loss), 2 (moderate to moderate severe hearing loss), and 3 (severe to profound hearing loss). In (a) perilymph (PL) and (b) cerebrospinal fluid samples from vestibular schwannoma (VS) patients (n = 28) and meningioma patients (n = 3) were included. In (c) VS tissue samples (VS patients n = 20) were included. PC1, PC2: principal components 1 and 2.