Table 1 Differences in the studied parameters between the non-PM and PM groups.
Non-PM group | PM group | P-value | ||
|---|---|---|---|---|
Eyes, n | 19 | 99 | ||
Age at baseline, years | 63.4 ± 9.6 | 66.9 ± 9.8 | 0.09† | |
AL at baseline, mm | 28.53 ± 0.94 | 29.49 ± 1.73 | 0.03* | |
Male sex, n (%) | 1 (5) | 26 (26) | 0.046†* | |
LogMAR BCVA | Baseline | 0.29 ± 0.34 | 0.52 ± 0.39 | 0.02* |
1-year | 0.12 ± 0.22 | 0.37 ± 0.40 | 0.01* | |
2-year | 0.20 ± 0.33 | 0.40 ± 0.43 | 0.02* | |
3-year | 0.28 ± 0.38 | 0.41 ± 0.42 | 0.10 | |
4-year | 0.28 ± 0.36 | 0.46 ± 0.41 | 0.07 | |
MNV location at baseline (extrafoveal/juxtafoveal/subfoveal), n | 6/0/13 | 23/20/56 | 0.67‡ | |
MNV size at baseline, mm2 | 0.42 ± 0.49 | 0.57 ± 0.65 | 0.52 | |
CRT at baseline, μm | 288.9 ± 107.3 | 291.1 ± 153.5 | 0.82 | |
CCT at baseline, μm | 74.2 ± 36.7 | 57.9 ± 22.3 | 0.06 | |
Number of injections, n | 1st year (0–1 year) | 2. 9 ± 1.3 | 1.9 ± 1.2 | 0.002* |
2nd year (1–2 years) | 0.9 ± 1.1 | 0.5 ± 1.0 | 0.02* | |
3rd year (2–3 years) | 0.6 ± 1.0 | 0.2 ± 0.7 | 0.002* | |
4th year (3–4 years) | 0.2 ± 0.5 | 0.2 ± 0.6 | 0.97 | |
Total (0–4 years) | 4.6 ± 2.6 | 2.9 ± 2.6 | 0.001* | |
Ratio of IVR against the total number of injections | 0.70 ± 0.45 | 0.59 ± 0.45 | 0.18 | |
No additional treatment, n (%) | 3 (16) | 35 (35) | 0.095† | |
ERM, n (%) | Baseline | 2 (11) | 20 (20) | 0.32† |
4-year | 3 (16) | 31 (31) | 0.17† | |
LMH, n (%) | Baseline | 0 (0) | 0 (0) | – |
4-year | 0 (0) | 3 (3) | 0.44† | |
Lens status, n (phakia/pseudophakia/aphakia) | Baseline | 14/5/0 | 67/31/1 | 0.82‡ |
4-year | 11/8/0 | 43/55/1 | 0.48‡ |