Figure 3

Leave-one-out cross validation (LOOCV) predictions using all metabolomics data for selected traits. Older age was strongly related to the metabolomics data with no differences between the LIFE and CON groups (r = 0.80, p = value = 5e−24). LIFE and CON group membership was strongly predicted using the plasma metabolomics data for three different body composition outcomes including BMI (r = 0.84, p-value = 3e−29), percent body fat (r = 0.80, p-value = 7e−24), and the sagittal abdominal diameter (SAD) (r = 0.82, p-value = 6e−27), and moderately predicted for the average number of daily servings of fruits and vegetables combined (r = 0.66, p-value = 3e−14), and the days per week for moderate-to-vigorous physical activity (MVPA) (r = 0.68, p-value = 4e−15).