Table 4 Hypomethylated DMRs overlapping homeobox genes that are only found in one TCGA cancer type.

From: Homeobox and Polycomb target gene methylation in human solid tumors

TCGA cancer

Gene

BLCA

ISL1, NOBOX

CESC

HOXA6, HOXA7, HOXA9, HOXC5, POU2F2

CHOL

MEIS2

ESCA squamous cell

BARHL2, HLX, EN1, HOXD12, HOXD11, HOXD10, HOXD9, HOXD8, GBX2, DLX6, EN2, DRGX, VAX1, EMX2, HMX3, GSX1, IRX3, HOXB7, HOXB8, HOXB9, ARX, RHOXF1

LIHC

PAX7, IRX4, PROP1, MNX1, PKNOX2, GSC2

THCA

PRRX1, LHX9, PROX1, SIX3, MEIS1, VAX2, CERS6, GSX2, HOPX, HMBOX1, PBX3, ZEB1, HHEX, PITX3, HMX2, PHOX2A, POU6F1, SIX1, SIX4, SEBOX, LHX1, DLX3, TGIF1, TSHZ1, RAX2, CERS4, SIX5, ADNP, PKNOX1, HDX

UCEC

TGIF2, OTX1, HOXA1, HOXA2, HOXC8

  1. The DMRs must have a greater than 0.2 difference in the beta value between tumor and normal tissue to meet this classification.