Figure 3

Mapping of the detected peptides in apolipoprotein E. The laser-microdissected amyloid samples from animals 4–8 are presented in the upper rows, and the three needle-microdissected amyloid samples from animal 7 are presented in the lower rows. When the total number of detected peptides increases, the color becomes redder. Of the full length of the 274 amino acid residues, Leu185–Arg230 is frequently detected. Black vertical lines mark the positions of non-tryptic truncation sites.