Table 2 Study-level heritability (h2) estimates for T2D among 8,240,835 overlapping variants.
From: Variant level heritability estimates of type 2 diabetes in African Americans
T2D Cases/Controls | Case proportion | Method | Model 1 | Model 2 | Model 3 | |
|---|---|---|---|---|---|---|
h2 (SE) | h2 (SE) | h2 (SE) | ||||
REGARDS | 2516/5996 | 0.30 | LDAK | 0.19 (0.05) | 0.18 (0.05) | 0.18 (0.05) |
GCTA | 0.25 (0.06) | 0.24 (0.06) | 0.24 (0.06) | |||
GenHAT | 2776/2722 | 0.50 | LDAK | 0.19 (0.08) | 0.19 (0.08) | 0.18 (0.08) |
GCTA | 0.21 (0.10) | 0.21 (0.10) | 0.21 (0.10) | |||
eMERGE | 2665/2660 | 0.50 | LDAK | 0.33 (0.08) | 0.33 (0.08) | 0.33 (0.08) |
GCTA | 0.31 (0.09) | 0.32 (0.09) | 0.32 (0.09) |
