Table 2 Comparative analysis of differences in ultrasound between the pCR group and Non-pCR group.

From: Predicting pathological complete response after neoadjuvant chemotherapy in breast cancer by clinicopathological indicators and ultrasound parameters using a nomogram

Factors

 

Before NACT

After 2 cycles of NACT

 

Non-pCR(108)

pCR(68)

P

Non-pCR(108)

pCR(68)

P

Form

Regular

3

2

0.949

10

8

0.593

Irregular

105

66

 

98

60

 

Adler grade*

Level 0

8

2

 

9

7

 
 

Level 1

25

14

0.426

38

26

0.909

 

Level 2

34

28

 

42

25

 
 

Level 3

41

24

 

19

10

 

Boundary

Circumscribed

38

26

0.682

9

5

0.815

 

Indistinct

70

42

 

99

5

 

Echo

Very low

8

8

 

5

4

 
 

Low

98

58

0.631

95

58

0.914

 

Mix

1

1

 

1

1

 
 

Wait for an echo

1

1

 

7

5

 

Posterior acoustic

Shadowing

14

10

0.184

39

28

0.124

 

No change

89

50

 

66

34

 
 

Enhancement

5

8

 

3

6

 

Calcification

None

50

32

0.921

41

26

0.971

 

Have

58

36

 

67

42

 
  1. *Adler grade: Level 0: no blood flow in the lesion; Level 1:a small amount of blood flow, with 1 or 2 punctured or thin rod blood flow; Level 2: moderate blood flow, one major blood vessel can be seen, its length is close to or beyond the radius of the lesion or 3 ~ 4 punctured or fine rod-shaped blood vessels; Level 3: abundant blood flow, visible more than 4 blood vessels or interconnected, intertwined into a network. Adler grading observes the distribution and richness of blood flow, finds the section with the most abundant blood flow, calculates the number of blood vessels. Te definition ofAlder grading change is whether grading decreases after NAC.