Table 1 Changes in sleep/wake rhythms in human P301S tau Tg mice at 7, 9, and 10 months old.
From: Effects of an OX2R agonist on migration and removal of tau from mouse brain
Age | Total time | Episode number | Episode duration | ||||||
|---|---|---|---|---|---|---|---|---|---|
Wake | NREM | REM | Wake | NREM | REM | Wake | NREM | REM | |
Dark period (active phase) | |||||||||
7 months old | – | – | – | ⇣ | – | – | – | – | – |
9 months old | – | – | – | ↓ | ↓ | – | ⇡ | – | – |
10 months old | ↑ | ↓ | – | ↓ | ↓ | – | ⇡ | – | – |
Light period (sleep phase) | |||||||||
7 months old | – | – | – | – | – | – | – | – | – |
9 months old | – | – | – | – | – | – | – | – | – |
10 months old | – | – | ↑ | – | – | ⇡ | – | – | – |
