Figure 6 | Scientific Reports

Figure 6

From: Predicting type 2 diabetes via machine learning integration of multiple omics from human pancreatic islets

Figure 6

Biological interpretation. (a) Circle plot demonstrating the most predictive features located at the poles of the circle and between-features connections across the three Omics (mRNA expression (expr), DNA methylation (meth), genetic variation/SNPs (gen)) as well as clinical phenotypes (phen). (b) Circos plot demonstrating what features across Omics (mRNA expression (expr), DNA methylation (meth), genetic variation/SNPs (gen)) as well as clinical phenotypes (phen) that are most tightly linked in a presumable biological pathway.

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