Table 2 Top ranked selected features included in the final integrative multiOmics model for T2D prediction.
Expression features | DNA methylation features | Genotype features | Phenotype features | ||
|---|---|---|---|---|---|
Gene name | Illumina ID | Nearest gene/region * | SNP ID | Nearest gene/region | |
ARG2 | cg00970981 | intergenic | rs13279576_A | LOC101929294 / intronic | Age |
ARL4C | cg02736232 | IRF8 / TSS1500 | rs7931183_A | ANO1 / intronic | Sex |
BARX1 | cg02966936 | intergenic | rs7430710_A | intronic | BMI |
CACNG5 | cg02988288 | TXNIP / 5'UTR | Stimulatory index (insulin secretion) | ||
CHL1 | cg03622758 | ZDHHC3 / TSS1500 | |||
CLTRN | cg03770217 | FAM109A / 5'UTR | |||
CNTN5 | cg04255401 | intergenic | |||
COMP | cg04577129 | intergenic | |||
CPXM2 | cg05627498 | intergenic | |||
DKK3 | cg06184251 | intergenic | |||
ELFN1 | cg07175985 | SACS / TSS200 | |||
FOXE1 | cg08248985 | ROR1 / 5'UTR | |||
FSTL4 | cg09216797 | INPP5A / 5'UTR | |||
FXYD2 | cg09449232 | RP11-266E14.1 / lincRNA | |||
GABRA2 | cg09467248 | intergenic | |||
GAD1 | cg11515284 | intergenic | |||
GCNT4 | cg12164242 | NCOR2 / 5'UTR | |||
GLRA1 | cg12220370 | RBFOX3 / 5'UTR | |||
GRAMD2B | cg12451325 | RP11-665G4.1 / antisense | |||
HCN4 | cg13336515 | intergenic | |||
KCNA1 | cg13566279 | intergenic | |||
LRRC2 | cg13970113 | intergenic | |||
LSAMP | cg14490520 | intergenic | |||
MPP1 | cg14527110 | P4HA2 / 5'UTR | |||
NEFL | cg14534405 | intergenic | |||
NIPAL4 | cg15630265 | SHANK2 / 3'UTR | |||
NOTUM | cg17826980 | intergenic | |||
OPRD1 | cg21165486 | MGST3 / 5'UTR | |||
PCOLCE2 | cg21533994 | SLC15A4 / TSS200,3'UTR | |||
PLA1A | cg25934997 | SYNPO / 5'UTR | |||
PRELP | cg25979005 | intergenic | |||
RASGRP1 | cg26445440 | intergenic | |||
REEP1 | cg26767974 | HDAC4 / 5'UTR | |||
RHOT1 | |||||
SLC24A2 | |||||
SLC2A2 | |||||
SV2B | |||||
TFCP2L1 | |||||
