Figure 5 | Scientific Reports

Figure 5

From: Caspase-4 in glioma indicates deterioration and unfavorable prognosis by affecting tumor cell proliferation and immune cell recruitment

Figure 5

Correlation between CASP4 and classical pyroptosis-related glioma genes. (A) Expression of recognized pyroptosis pathway-related genes in LGG and GBM. (B) Protein–protein interaction analysis of CASP4 and classical pyroptosis-related genes; number of nodes = 8, number of edges = 26, average node degree = 6.5, avg. local clustering coefficient = 0.94, PPI enrichment P-value < 1.0e−16. (C) Correlation between expression of CASP4 and classical pyroptosis-related genes in LGG. (D) Correlation between expression of CASP4 and classical pyroptosis genes in GBM. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 and ns, no significant difference (P > 0.05). The significance of differences between groups of samples was evaluated by Wilcox tests (2 groups) and Kruskal–Wallis analysis (≥ 3 groups).

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