Figure 7 | Scientific Reports

Figure 7

From: Caspase-4 in glioma indicates deterioration and unfavorable prognosis by affecting tumor cell proliferation and immune cell recruitment

Figure 7

Distribution of tumor-infiltrating immune cells in glioma and their correlation with CASP4 expression. (A) Correlation between CASP4 and six tumor-infiltrating immune cell types in LGG and GBM. (B) Percentages of 22 immune cells in glioma patients determined using the CIBERSORT algorithm. (C) Percentage differentiation of 22 immune cells in patients with high and low CASP4 expression. (D) ESTIMATE algorithm results for relationship between high and low CASP4 expression with immune cells and immune scores (E). (F) Genes associated with the seven steps of antitumor immunity. (G) Correlation between CASP4 expression and the seven steps of anti-tumor immunity. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 and ns, no significant difference (P > 0.05).

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