Figure 2

MPTP-induced behavioral alteration of mice in the open-field locomotion (A), catalepsy (C), and wire-hanging test (D). (B) Representative examples of moving pattern from each group of mice. MPTP mice were received (i.p.) 30 mg/kg MPTP-HCl daily for 5 consecutive days (MPTP and MPTP + P). Probiotic mice were administered 1 dose (108 CFU/mouse/day) daily of L. rhamnosus E9 for fifteen days and sacrificed after the last dose (P and MPTP + P). filled circle, control; filled square, P; filled triangle, MPTP; filled diamond, MPTP + P. *p ≤ 0.05, control vs MPTP (n:6/group).