Figure 3

Impact of Lacticaseibacillus rhamnosus E9 administration on striatal Tyrosine hydroxylase (TH) protein (A, B) and gene (C) expression level and dopamine level (D) in MPTP-induced mouse model of PD compared to the control. MPTP mice were received (i.p.) 30 mg/kg MPTP-HCl daily for 5 consecutive days (MPTP and MPTP + P). Probiotic mice were administered 1 dose (108 CFU/mouse/day) daily of L. rhamnosus E9 for fifteen days and sacrificed after the last dose (P and MPTP + P). *p ≤ 0.05, control vs MPTP (n:4–5/group).