Figure 4 | Scientific Reports

Figure 4

From: A neurotherapeutic approach with Lacticaseibacillus rhamnosus E9 on gut microbiota and intestinal barrier in MPTP-induced mouse model of Parkinson’s disease

Figure 4

Impact of Lacticaseibacillus rhamnosus E9 administration on striatal gene expression of Dopamine Receptor 1 (DR1), Dopamine Receptor 2 (DR2), and Dopamine Transporter (DAT) and Reactive Oxygen Species (ROS) in MPTP-induced mouse model of PD compared to the control. MPTP mice were received (i.p.) 30 mg/kg MPTP-HCl daily for 5 consecutive days (MPTP and MPTP + P). Probiotic mice were administered 1 dose (108 CFU/mouse/day) daily of L. rhamnosus E9 for fifteen days and sacrificed after the last dose (P and MPTP + P). *p ≤ 0.05, control vs MPTP (n:4–5/group).

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