Figure 4
From: A novel insight into neurological disorders through HDAC6 protein–protein interactions
Chord diagram of the reported alterations in response to HDAC6 inhibition. In this diagram, each link represents a reported alteration in the expression levels, post-translational modification, degradation, activity, or transport of the corresponding protein/gene after HDAC6 inhibition. The reported alterations in mRNA/protein expression and phosphorylation levels were further divided into increased ( +) and decreased (−). Note that “other” associations (colored in brown) include changes in DNA binding and promoter activity.
