Figure 3

Mutation patterns detected in the URA5.3 gene in 5-FOA-resistant strains. Panel (a) mutation patterns in 24 5-FOA-resistant strains obtained by high-energy neutron (left) and in 20 5-FOA-resistant strains obtained by thermal neutron (right) irradiation. The indicated mutation patterns are shown in %. Panel (b) characterization of single-base substitution. The single-base substitutions shown in panel (a) (28 and 17 sites in 5-FOA-resistant strains by high-energy and thermal neutron irradiation, respectively) are classified into transition and transversion, and their contents are indicated (left, high-energy neutron; right, thermal-energy neutron). The indicated number denotes % of each category.