Table 4 Cox proportional hazards regression analysis for the risk of herpes zoster in different type of obesity.
From: The risk of herpes zoster is positively associated with obesity, especially morbid obesity
Variables | Obesity | cHR | (95% CI) | p-value | aHR | (95% CI) | p-value | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Non-morbid obesity | Morbid obesity | |||||||||||
Event | PY | IR | Event | PY | IR | |||||||
Gender | ||||||||||||
Female | 649 | 78,179 | 8.30 | 71 | 10,710 | 6.63 | 1.06 | (0.83, 1.35) | 0.66 | 1.36 | (1.06, 1.74)* | 0.02 |
Male | 341 | 50,015 | 6.82 | 54 | 7906 | 6.83 | 1.38 | (1.04, 1.84)* | 0.03 | 1.66 | (1.24, 2.23)*** | < 0.001 |
Age, year | ||||||||||||
20–29 | 72 | 21,997 | 3.27 | 17 | 5171 | 3.29 | 1.29 | (0.76, 2.19) | 0.35 | 1.30 | (0.76, 2.20) | 0.34 |
30–39 | 155 | 31,845 | 4.87 | 26 | 5819 | 4.47 | 1.27 | (0.83, 1.93) | 0.27 | 1.28 | (0.84, 1.95) | 0.25 |
40–49 | 215 | 31,105 | 6.91 | 33 | 3898 | 8.47 | 1.55 | (1.07, 2.24)* | 0.02 | 1.59 | (1.10, 2.30)* | 0.01 |
≥ 50 | 548 | 43,246 | 12.67 | 49 | 3729 | 13.14 | 1.62 | (1.21, 2.18)** | 0.00 | 1.58 | (1.18, 2.12)** | 0.00 |
Comorbidities | ||||||||||||
Without comorbidities | 521 | 84,674 | 6.15 | 74 | 13,002 | 5.69 | 1.16 | (0.91, 1.48) | 0.23 | 1.40 | (1.10, 1.80)** | 0.01 |
With comorbiditiesa | 469 | 43,519 | 10.78 | 51 | 5614 | 9.08 | 1.39 | (1.04, 1.87)* | 0.03 | 1.57 | (1.17, 2.11)** | 0.00 |
DM | ||||||||||||
No | 655 | 97,152 | 6.74 | 92 | 14,423 | 6.38 | 1.20 | (0.97, 1.50) | 0.10 | 1.48 | (1.18, 1.84)*** | < 0.001 |
Yes | 335 | 31,042 | 10.79 | 33 | 4193 | 7.87 | 1.24 | (0.87, 1.78) | 0.24 | 1.47 | (1.02, 2.12)* | 0.04 |
CKD | ||||||||||||
No | 968 | 126,485 | 7.65 | 122 | 18,392 | 6.63 | 1.16 | (0.96, 1.41) | 0.11 | 1.45 | (1.20, 1.75)*** | < 0.001 |
Yes | 22 | 1708 | 12.88 | 3 | 224 | 13.39 | 2.23 | (0.63, 7.86) | 0.21 | 2.61 | (0.69, 9.83) | 0.16 |
CAD | ||||||||||||
No | 735 | 108,854 | 6.75 | 93 | 16,107 | 5.77 | 1.13 | (0.91, 1.40) | 0.28 | 1.42 | (1.14, 1.76)** | 0.00 |
Yes | 255 | 19,340 | 13.19 | 32 | 2510 | 12.75 | 1.55 | (1.07, 2.25)* | 0.02 | 1.62 | (1.11, 2.35)* | 0.01 |
Cancer | ||||||||||||
No | 965 | 125,649 | 7.68 | 121 | 18,324 | 6.60 | 1.16 | (0.96, 1.40) | 0.13 | 1.45 | (1.20, 1.76)*** | < 0.001 |
Yes | 25 | 2544 | 9.83 | 4 | 292 | 13.70 | 2.83 | (0.93, 8.58) | 0.07 | 2.36 | (0.74, 7.52) | 0.14 |