Table 1 Plasma parameters of dams at PP30.

From: Postpartum development of metabolic dysfunction-associated steatotic liver disease in a lean mouse model of gestational diabetes mellitus

 

LF

N = 10

HF

N = 12

GDM

N = 13

LF vs. HF

LF vs. GDM

HF vs. GDM

ALT (U/L)

71.50 ± 18.42

63.75 ± 13.51

155.00 ± 61.61

ns

0.0015

0.0002

AST (U/L)

24.00 ± 6.99

26.67 ± 22.09

81.92 ± 45.26

ns

0.0009

 < 0.0001

Cholesterol (mM/L)

2.48 ± 0.39

2.88 ± 0.42

2.76 ± 0.27

0.0462

ns

ns

Triglycerides (mM/L)

0.44 ± 0.17

0.39 ± 0.19

0.41 ± 0.23

ns

ns

ns

NEFAs (mM/L)

0.45 ± 0.11

0.70 ± 0.24

0.70 ± 0.27

0.0193

0.0121

ns

Leptin (ng/ml)

19.75 ± 9.20

25.96 ± 10.28

18.21 ± 7.63

ns

ns

ns

  1. Data are presented as the mean ± SD. Statistical analysis was performed using Kruskal–Wallis test, followed by Dunn’s multiple comparison test. P values are presented as group comparisons.
  2. LF low-fat diet, HF high-fat diet, GDM gestational diabetes mellitus, AST plasma aspartate transaminase, ALT plasma alanine aminotransferase.
Back to article page