Table 1 Baseline clinical characteristics associated with distant metastasis in gastric cancer patients.

From: A nomogram combining neutrophil to lymphocyte ratio (NLR) and prognostic nutritional index (PNI) to predict distant metastasis in gastric cancer

Variable

M1 (n = 280)

M0 (n = 1001)

p-value

Sex

Female

126 (45%)

407 (40.7%)

0.217

Male

154 (55%)

594 (59.3%)

 

Age (years)

 

\(56.1 \pm 11.7\)

\(56.8\pm 10.9\)

0.337

White blood cell count \((10^9/{\text{L}})\)

 

\(6.3 \pm 2.3\)

\(5.4 \pm 1.6\)

< 0.001

Red blood cell count \((10^{12}/{\text{L}})\)

 

\(4.0 \pm 0.6\)

\(4.2 \pm 0.6\)

< 0.001

Hemoglobin (g/L)

\(\ge 120\)

125 (44.6%)

647 (64.6%)

< 0.001

< 120

155 (55.4%)

354 (35.4%)

 

Platelet count \((10^9/{\text{L}})\)

 

\(258.2 \pm 105.4\)

\(219.7\pm 73.9\)

< 0.001

Neutrophil count \((10^9/{\text{L}})\)

 

\(4.3 \pm 2.1\)

\(3.2 \pm 1.4\)

< 0.001

Lymphocyte count \((10^9/{\text{L}})\)

 

\(1.3 \pm 0.5\)

\(1.6\pm 0.6\)

< 0.001

Monocyte count \((10^9/{\text{L}})\)

 

\(0.5 \pm 0.2\)

\(0.4\pm 0.2\)

< 0.001

Total protein (g/L)

\(\ge 60\)

208 (74.3%)

835 (83.4%)

< 0.001

< 60

72 (25.7%)

166 (16.6%)

 

Albumin (g/L)

\(\ge 35\)

210 (75%)

889 (88.8%)

< 0.001

< 35

70 (25%)

112 (11.2%)

 

d-dimer (mg/L)

\(\le 0.5\)

178 (63.6%)

934 (93.3%)

< 0.001

> 0.5

102 (36.4%)

67 (6.7%)

 

CEA (ng/mL)

\({\le 5}\)

204 (72.9%)

938 (93.7%)

< 0.001

> 5

76 (27.1%)

63 (6.3%)

 

CA199 (U/mL)

\({\le 35}\)

177 (63.2%)

908 (90.7%)

< 0.001

> 35

103 (36.8%)

93 (9.3%)

 

CA125 (U/mL)

\({\le 35}\)

173 (61.8%)

979 (97.8%)

< 0.001

> 35

107 (38.2%)

22 (2.2%)

 

NLR

\({\le 2.023}\)

57 (20.4%)

551 (55%)

< 0.001

> 2.023

223 (79.6%)

450 (45%)

 

PLR

\({\le 174.461}\)

111 (39.6%)

707 (70.6%)

< 0.001

> 174.461

169 (60.4%)

294 (29.4%)

 

LMR

\({\le 2.732}\)

133 (47.5%)

202 (20.2%)

< 0.001

> 2.732

147 (52.5%)

799 (79.8%)

 

SII

\({\le 558.746}\)

99 (35.4%)

720 (71.9%)

< 0.001

> 558.746

181 (64.6%)

281 (28.1%)

 

PNI

\({\le 45.250}\)

169 (60.4%)

338 (33.8%)

< 0.001

> 45.250

111 (39.6%)

663 (66.2%)

 

Metastasis site

Peritoneum

111

  

Liver

48

  

Lymph nodes

16

  

Bone

10

  

Ovary

5

  

Lung

2

  

Multiple

88

  
  1. M1: patients with distant metastasis; M0: patients without distant metastasis; lymph nods: distant lymph node metastasis beyond regional lymph nodes; multiple: two or more distant metastasis sites.