Table 2 Baseline clinical characteristics of patients in training set and validation set and univariate analysis in training set.

Sex

Female

363 (40.5%)

170 (44.2%)

0.250

85 (42.9%)

278 (39.8%)

0.482

Male

533 (59.5%)

215 (55.8%)

113 (57.1%)

420 (60.2%)

Age (years)

\(56.7 \pm 11.2\)

\(56.5 \pm 10.8\)

0.797

\(55.9 \pm 11.4\)

\(56.9 \pm 11.2\)

0.275

White blood cell count \((10^9/{\text{L}})\)

\(5.6\pm 1.9\)

\(5.6 \pm 1.8\)

0.964

\(6.4\pm 2.3\)

\(5.4 \pm 1.7\)

\(< 0.001\)

Red blood cell count \((10^{12}/{\text{L}})\)

\(4.1\pm 0.6\)

\(4.2 \pm 0.6\)

0.317

\(4.0\pm 0.6\)

\(4.2 \pm 0.6\)

\(< 0.001\)

Hemoglobin (g/L)

\(\ge 120\)

535 (59.7%)

237 (61.6%)

0.577

83 (41.9%)

452 (64.8%)

< 0.001

\(< 120\)

361 (40.3%)

148 (38.4%)

115 (58.1%)

246 (35.2%)

Platelet count \((10^9/{\text{L}})\)

\(228.7\pm 85.9\)

\(226.7 \pm 77.0\)

0.671

\(265.3 \pm 111.9\)

\(218.3 \pm 73.8\)

\(< 0.001\)

Neutrophil count \((10^9/{\text{L}})\)

\(3.5\pm 1.6\)

\(3.5 \pm 1.6\)

0.939

\(4.4\pm 2.1\)

\(3.2 \pm 1.4\)

\(< 0.001\)

Lymphocyte count \((10^9/{\text{L}})\)

\(1.5\pm 0.6\)

\(1.5 \pm 0.5\)

0.957

\(1.3\pm 0.5\)

\(1.6 \pm 0.6\)

\(< 0.001\)

Monocyte count \((10^9/{\text{L}})\)

\(0.4\pm 0.2\)

\(0.4 \pm 0.2\)

0.829

\(0.5\pm 0.2\)

\(0.4 \pm 0.2\)

0.002

Total protein (g/L)

\(\ge 60\)

723 (80.7%)

320 (83.1%)

0.345

152 (76.8%)

571 (81.8%)

0.138

\(< 60\)

173 (19.3%)

65 (16.9%)

46 (23.2%)

127 (18.2%)

Albumin (g/L)

\(\ge 35\)

760 (84.8%)

339 (88.1%)

0.152

151 (76.3%)

609 (87.2%)

< 0.001

\(< 35\)

136 (15.2%)

46 (11.9%)

47 (23.7%)

89 (12.8%)

d-dimer (mg/L)

\(>0.5\)

123 (13.7%)

46 (11.9%)

0.440

123 (62.1%)

650 (93.1%)

< 0.001

\(\le 0.5\)

773 (86.3%)

339 (88.1%)

75 (37.9%)

48 (6.9%)

CEA (ng/mL)

\({\le 5}\)

797 (89%)

345 (89.6%)

0.803

143 (72.2%)

654 (93.7%)

< 0.001

> 5

99 (11%)

40 (10.4%)

55 (27.8%)

44 (6.3%)

CA199 (U/mL)

\({\le 35}\)

761 (84.9%)

324 (84.2%)

0.787

122 (61.6%)

639 (91.5%)

< 0.001

> 35

135 (15.1%)

61 (15.8%)

76 (38.4%)

59 (8.5%)

CA125 (U/mL)

\({\le 35}\)

806 (90%)

346 (89.9%)

1.000

124 (62.6%)

682 (97.7%)

< 0.001

> 35

90 (10%)

39 (10.1%)

74 (37.4%)

16 (2.3%)

NLR

\({\le 2.023}\)

420 (46.9%)

188 (48.8%)

0.561

34 (17.2%)

386 (55.3%)

< 0.001

> 2.023

476 (53.1%)

197 (51.2%)

164 (82.8%)

312 (44.7%)

PLR

\({\le 174.461}\)

578 (64.5%)

240 (62.3%)

0.498

78 (39.4%)

500 (71.6%)

< 0.001

> 174.461

318 (35.5%)

145 (37.7%)

120 (60.6%)

198 (28.4%)

LMR

\({\le 2.732}\)

238 (26.6%)

97 (25.2%)

0.659

98 (49.5%)

140 (20.1%)

< 0.001

> 2.732

658 (73.4%)

288 (74.8%)

100 (50.5%)

558 (79.9%)

SII

\({\le 558.746}\)

572 (63.8%)

247 (64.2%)

0.964

67 (33.8%)

505 (72.3%)

< 0.001

> 558.746

324 (36.2%)

138 (35.8%)

131 (66.2%)

193 (27.7%)

PNI

\({\le 45.250}\)

358 (40%)

149 (38.7%)

0.720

122 (61.6%)

236 (33.8%)

< 0.001

> 45.250

538 (60%)

236 (61.3%)

76 (38.4%)

462 (66.2%)

Metastasis

M0

698 (77.9%)

303 (78.7%)

0.807

M1

198 (22.1%)

82 (21.3%)