Table 9 Cognitive functioning 5 years post-baseline.

From: Five-year follow-up of the OptiTrain trial on concurrent resistance and high-intensity interval training during chemotherapy for patients with breast cancer

Amsterdam cognition Scan (ACS)

 

Baseline

Mean ± SD

 

Between-group differences

Mean difference (95% CI)

ES

Wordlist learning (Total numbers correct)

RT-HIIT

49.39 ± 6.97

RT-HIIT versus UC

2.11 (− 6.83, 11.04)

0.22

AT-HIIT

47.12 ± 14.15

AT-HIIT versus UC

− 0.17 (− 8.96, 8.63)

− 0.02

UC

47.29 ± 9.64

   

Wordlist recall (Total numbers correct)

RT-HIIT

9.67 ± 3.45

RT-HIIT versus UC

1.17 (− 1.74, 4.08)

0.31

AT-HIIT

9.22 ± 3.70

AT-HIIT versus UC

0.72 (− 2.05, 3.49)

0.19

UC

8.50 ± 3.81

   

Wordlist recognition (Total numbers correct)

RT-HIIT

29.10 ± 1.09

RT-HIIT versus UC

− 0.09 (− 0.95, 0.76)

− 0.09

AT-HIIT

29.19 ± 1.11

AT-HIIT versus UC

− 0.00 (− 0.82, 0.81)

0

UC

29.19 ± 0.98

   

Box tapping (Total numbers correct)

RT-HIIT

8.41 ± 2.22

RT-HIIT versus UC

− 0.40 (− 1.86, 1.05)

− 0.21

AT-HIIT

8.30 ± 1.44

AT-HIIT versus UC

− 0.52 (− 1.92, 0.88)

− 0.27

UC

8.81 ± 1.91

   

Digit sequences I (Total numbers correct)

RT-HIIT

10.65 ± 2.10

RT-HIIT versus UC

0.71 (− 1.03, 2.46)

0.30

AT-HIIT

9.81 ± 2.27

AT-HIIT versus UC

− 0.12 (− 1.81, 1.57)

− 0.06

UC

9.94 ± 2.35

   

Digit sequences II (Total numbers correct)

RT-HIIT

8.26 ± 2.63

RT-HIIT versus UC

− 0.05 (− 2.06, 1.96)

− 0.18

AT-HIIT

8.12 ± 2.32

AT-HIIT versus UC

− 0.20 (− 1.96, 2.06)

− 0.07

UC

8.31 ± 2.85

   

Reaction speed (Reaction time in ms)a

RT-HIIT

315.54 ± 57.63

RT-HIIT versus UC

− 10.92 (− 52.59, 30.76)

− 0.17

AT-HIIT

311.36 ± 40.87

AT-HIIT versus UC

− 15.09 (− 55.11, 24.92)

− 0.24

UC

326.46 ± 63.14

   

Connect the dots I (Completion time in s) a

RT-HIIT

40.57 ± 6.71

RT-HIIT versus UC

1.47 (− 4.79, 7.74)

0.17

AT-HIIT

42.46 ± 8.07

AT-HIIT versus UC

3.37 (− 2.95, 9.68)

0.40

UC

39.10 ± 8.49

   

Connect the dots II (Completion time in s) a

RT-HIIT

72.77 ± 17.60

RT-HIIT versus UC

− 1.79 (− 15.70, 12.13)

− 0.07

AT-HIIT

67.07 ± 12.03

AT-HIIT versus UC

− 7.48 (− 21.17, 6.21)

− 0.31

UC

74.55 ± 23.87

   

Place the beads (Number of extra moves) a

RT-HIIT

31.74 ± 16.95

RT-HIIT versus UC

5.11 (− 6.35, 16.58)

0.54

AT-HIIT

27.63 ± 15.07

AT-HIIT versus UC

1.00 (− 10.11, 12.12)

0.11

UC

26.63 ± 9.46

   

Fill the grid (Completion time in s)a

RT-HIIT

68.16 ± 12.97

RT-HIIT versus UC

− 1.22 (− 11.93, 9.49)

− 0.10

AT-HIIT

73.20 ± 13.77

AT-HIIT versus UC

3.82 (− 6.46, 14.09)

0.31

UC

69.38 ± 12.36

   
  1. SD Standard deviation, CI Confidence interval, RT-HIIT Resistance training and high-intensity interval exercise group, AT-HIIT Moderate-intensity and high-intensity interval training group, UC Usual care. a Higher scores indicate worse performance.
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