Figure 1
Results from the GWAS. (a) Manhattan plot representing results from the GWAS on oral microbial features. The red line represents the genome-wide significance level (P = 5 × 10–8) and the blue line represents study-wide significance level (P = 5 × 10–8 / 44). The rsID and nearest gene annotation is identified and included using topR R package. The color-coding represents 6/44 bacterial features that had variants reaching genome-wide significance level (P < 5 × 10–8). (b) Box plots representing the genetic effect of SNPs identified to significantly associate with abundance of bacterial taxa. The box plot displays the lower quartile, median, and upper quartile values within a box.
