Figure 3

EcPDF expression increases tumorigenicity in the in vivo xenograft model. (A) In vivo subcutaneous tumor growth curves of control and EcPDF3f SW480 cells. Tumor volumes were subsequently measured every 2 days until day 26. Data in the graph are presented as the mean ± SD of five mice per sample; two-tailed t-test; significant P values are indicated in the figure. (B) Representative image of xenograft mice on day 26 post-injection. (C) Images of the control and EcPDF3f SW480 xenograft tumors dissected from five different mice (#1–5) on day 26 post-injection. (D) The weights of the xenograft tumors in (C). Error bars are presented as the mean ± SD of five xenograft tumors per sample; two-tailed t-test; significant P value is indicated in the figure. (E) Same as in (C) but immunoblotting of EcPDF3f.