Table 2 Analysis of rs17713054 genotypes and alleles association with COVID-19 severity under five different inheritance models.
Genotypes/Alleles | Case group n = 100 (%) | Control group n = 151 (%) | Model of Inheritance | P-values | OR (95% CI)* | AIC* | BIC* |
|---|---|---|---|---|---|---|---|
GG | 70 (70%) | 120 (79.5%) | – | 87 × 10–2 | 0.603 (0.337–1.079) | _ | |
GA | 24 (24%) | 31 (20.5%) | 2.93 × 10–1 | 1.222 (0.667–2.24) | |||
AA | 6 (6%) | 0 | 8 × 10–3 | 11.2 (1.357–92.46) | |||
G | 164 (82%) | 271 (89.7%) | 0.013 | 1.919 (1.143–3.221) | |||
A | 36 (18%) | 31 (10.3%) | |||||
– | – | – | Log-Additive | 0.016 | 0.53 (0.32–0.89) | 335.7 | 342.8 |
GG-AA | 120(79.5%) | 76(76%) | Over-Dominant | 0.52 | 1 | 341.1 | 348.2 |
GA | 31(20.5%) | 24(24%) | 0.82 (0.45–1.5) | ||||
GG | 120 (79.5) | 70 (70) | Co-Dominant | 0.0024 | 1.00 | 331.4 | 342 |
GA | 31 (20.5) | 24 (24) | 0.75 (0.41–139) | ||||
AA | 0 | 6 (6) | 0.00 | ||||
GG | 120 (79.5) | 70 (70) | Dominant | 0.089 | 1.00 | 338.6 | 346 |
GA-AA | 31 (20.5) | 30 (30) | 0.6 (0.34–1.08) | ||||
GG-GA | 151 (100) | 94 (94) | Recessive | 0.0008 | 1.00 | 330.3 | 337 |
AA | 0 | 6 (6) | 0.00 | ||||
