Figure 7
Establishment of diabetic cardiomyopathy mouse model and validation of hub genes and ROC analysis. Schematic illustration of diabetic cardiomyopathy mouse model. (B,C) Body weight, and random blood glucose, at 7 weeks after STZ injection (n = 6 each). (D) ROC curve analysis of Pdk4, Igf1r, Lipe, Serpine1 and Bcl2l1 in the merged dataset. (E) Gene expression in a mouse model of DCM and Con. ****P < 0.0001, ***P < 0.001, **P < 0.01, *P < 0.05. (F) ROC curve analysis of Pdk4, Igf1r, Lipe, Serpine1 and Bcl2l1 in the validating dataset GSE5606. (G) ROC curve analysis of Pdk4, Igf1r, Lipe, Serpine1 and Bcl2l1 in the validating dataset GSE36875.
