Table 1 Confocal features and their definitions.

From: Reflectance confocal microscopy for plaque psoriasis therapeutic follow-up during an anti-interleukin-17A monoclonal antibody: an observational study

RCM features

Definition

Parakeratosis

The presence of nucleated cells in the stratum corneum is visualized as bright nuclei in dark corneocytes

Acanthosis (epidermal thickness)

Evaluated using VivaStack software analysis considering all cellulated layers until the total appearance of the dermal fibers

Inflammatory cells in the epidermis

The presence of bright, round-to-polygonal cells in the epidermis

Non-edge DP

Presence of dark dermal papillae more enlarged, not surrounded by bright ring of basal keratinocytes, and adjacent to each other, separated by a thin septum with a coarse fibrillary material

Vascularization in the papillary dermis

Round-to-canalicular dark structures with thin walls, inside the DP with multilocular appearance, at the level of the papillary dermis

Inflammatory cells in the dermis

The presence of bright or mildly refractive, round-to-polygonal cells around blood vessels in the dermis