Table 6 Subsets of these seven reactions can fulfill 236 cases.
From: Systematic analysis of microorganisms’ metabolism for selective targeting
Reactions abbreviation | Details | ||
|---|---|---|---|
PGI | GPR | pgi | |
Protein | Glucose-6-phosphate isomerase | ||
Pathway | Glycolysis/Gluconeogenesis | ||
Known drug | 5-Phosphoarabinonic acid | ||
PGK | GPR | pgk | |
Protein | Phosphoglycerate kinase | ||
Pathway | Glycolysis/Gluconeogenesis | ||
Known drug | – | ||
TPI | GPR | tpiA | |
Protein | Triose-phosphate isomerase | ||
Pathway | Glycolysis/Gluconeogenesis | ||
Known drug | – | ||
FBA | GPR | fbaA or fbaB | |
Protein | Fructose-bisphosphate aldolase class I & II | ||
Pathway | Glycolysis/Gluconeogenesis | ||
Known drug | Phosphoglycolohydroxamic Acid | ||
GND | GPR | gnd | |
Protein | 6-phosphogluconate dehydrogenase | ||
Pathway | Pentose Phosphate Pathway | ||
Known drug | – | ||
TKT2 | GPR | tktA or tktB | |
Protein | Transketolase | ||
Pathway | Pentose Phosphate Pathway | ||
Known drug | Cocarboxylase | ||
PGL | GPR | pgl | |
Protein | 6-phosphogluconolactonase | ||
Pathway | Pentose Phosphate Pathway | ||
Known drug | Formic acid | ||
