Table 1 IC50 values of 2 and 6 against glycogen synthase kinase α and β (GSK-3α and β).
From: Synthesis and preliminary evaluation of novel PET probes for GSK-3 imaging
Compound | IC50 GSK-3α (nM) | IC50 GSK-3β (nM) |
|---|---|---|
2 | 29.24 ± 2.93 (n = 3) | 24.29 ± 2.67 (n = 3) |
6 | 55.66 ± 4.89 (n = 3) | 43.99 ± 2.84 (n = 3) |
