Figure 6 | Scientific Reports

Figure 6

From: Down-regulation of SLC14A1 in prostate cancer activates CDK1/CCNB1 and mTOR pathways and promotes tumor progression

Figure 6

Single-cell transcriptomic analysis reveals that SLC14A1 expression is closely associated with prostate basal-type cells. (a) A heatmap of analysis of single-cell transcriptomic sequencing data of adult prostate in the GRNdb database (http://www.grndb.com/), which indicates SLC14A1 expression was mainly enriched in the SL00A2 + cluster. (b) GO enrichment analysis of the relative genes in the DisGeNET database (http://www.disgenet.org). (c) A heatmap shows analysis of the prostate single-cell transcriptome sequencing data from the THPA database (www.proteinatlas.org), which indicates SLC14A1 was mainly associated with prostate basal cells. (d) The transcription level of SLC14A1 in different normal tissues and organs of the human body. *only for annotation purpose. (e) mRNA expression of SLC14A1 across TCGA cancers with tumor and normal samples by the analysis from UALCAN website (https://ualcan.path.uab.edu/).

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