Figure 7
From: Activation of hTREK-1 by polyunsaturated fatty acids involves direct interaction
PUFAs activate TREK-1 in inside-out configuration of patch-clamp. (A–C) Representative traces showing the activation and reversibility in inside-out configuration of patch-clamp technique for (A) ML402 10 µM (B) C18:2 n-6 5 µM and (C) C22:6 n-3 5 µM superfused at the inner face of the membrane. Membrane potential was held at + 30 mV. The expanded current traces where extracted at the time indicated by the arrows.
