Table 1 Fatty acids nomenclature, characteristics and effects on the TREK-1 current in whole-cell configuration of patch-clamp.
From: Activation of hTREK-1 by polyunsaturated fatty acids involves direct interaction
IUPACName | Tail length | Unsaturation number | ω | IPUFA/I0 | IPUFA(pA/pF) | ||
|---|---|---|---|---|---|---|---|
C18:0 | Stearic acid | 18:0 | 18 | 0 | 1.0 ± 0.1 | 18.4 ± 0.5 | |
C18:1n-9 | Oleic acid (9) | 18:1Δ9 | 18 | 1 | ω-9 | 7.4 ± 1.9 | 113.1 ± 24.6 |
C18:2n-6 | Linoleic acid (9, 12) | 18:2Δ9,12 | 18 | 2 | ω-6 | 24.8 ± 3.3 | 353.7 ± 22.4 |
C18:3n-3 | Α-Linolenic acid (9, 12, 15) | 18:3Δ9,12,15 | 18 | 3 | ω-3 | 1.4 ± 0.1 | 20.72 ± 4.2 |
C20:2n-6 | Eicosadienoic acid (11,14) | 20:2Δ11,14 | 20 | 2 | ω-6 | 10.1 ± 1.2 | 166.1 ± 16.2 |
C20:4n-3 | Eicosatetraenoic acid (18,11,14,17) | 20:4Δ8,11,14,17 | 20 | 4 | ω-3 | 10.9 ± 2.0 | 119.2 ± 15.5 |
C20:4n-6 | Eicosatetraenoic acid (5,8,11,14) | 20:4Δ5,8,11,14 | 20 | 4 | ω-6 | 15.7 ± 2.1 | 199.5 ± 23.1 |
C20:5n-3 | Eicosatetraenoic acid (5,8,11,14,17) | 20:5Δ5,8,11,14,17 | 20 | 5 | ω-3 | 17.4 ± 2.8 | 211.7 ± 21.0 |
C22:5n-6 | Docosatetraenoic acid (4,7,10,13,16) | 20:5Δ4,7,10,13,16 | 22 | 5 | ω-6 | 26.1 ± 8.3 | 245.3 ± 21.4 |
C22:5n-3 | Docosatetraenoic acid (7,10,13,16,19) | 20:5Δ7,10,13,16,19 | 22 | 5 | ω-3 | 13.3 ± 2.9 | 147.1 ± 26.6 |
C22:6n-3 | Docosatetraenoic acid (4,7,10,13,16,19) | 20:6Δ4,7,10,13,16,19 | 22 | 6 | ω-3 | 29.8 ± 4.4 | 276.8 ± 24.5 |
