Table 1 Demographics and baseline clinical characteristics of patients with ocular syphilis.

From: Influence of gender on clinical presentation, management practices and outcomes of ocular syphilis

Characteristic

All (n = 127)

Women (n = 31)

Men (n = 96)

p value

Age (years) at diagnosis,

Mean ± SD (median, range)

46.6 ± 13.5 (48.0, 22–88)

40.0 ± 12.5 (50.0, 24–70)

45.83 ± 13.7 (47, 22–88)

0.256*

HIV-positive, n (%)

[n = 104, 25 women, 79 men]

36 (34.6)

3 (12.0)

33 (41.8)

0.006†

Bilateral involvement

87 (68.5)

22 (71.0)

65 (67.7)

0.734†

Duration (months) of symptoms at diagnosis,

Mean ± SD

[n = 123, 30 women, 93 men]

2.8 ± 6.3

1.8 ± 2.7

3.1 ± 7.1

0.252‡

Positive serum treponemal test, n (%)

127 (100)

31 (100)

96 (100)

NA

Titer of serum non-treponemal test,

 ≤ 1:128, n (%)

1:64

(1:1–1:2048)

55 (43.3)

1:64

(1:1–1:2048)

13 (41.9)

1:128

(1:1–1:1024)

42 (43.8)

0.435‡

0.859†

CSF abnormality, n (%)

[n = 85, 16 women, 69 men]

29 (34.1)

4 (25.0)

25 (36.2)

0.393†

Corticosteroid treatment

[n = 122, 30 women, 92 men]

74 (60.7)

14 (46.7)

60 (65.2)

0.071†

  1. n = 127 patients, 31 women and 96 men, unless otherwise stated
  2. NA not applicable, SD standard deviation, CSF cerebrospinal fluid.
  3. * Student’s t-test.
  4. Pearson’s chi square test.
  5. Mann–Whitney U test.