Table 2 Presenting ocular features in patients with ocular syphilis.

From: Influence of gender on clinical presentation, management practices and outcomes of ocular syphilis

Ocular feature

All (n = 214)

Women (n = 53)

Men (n = 161)

p value

Anatomic classification of uveitis23, n (%) [n = 212 eyes: 51 eyes of women, 161 eyes of men]‡

 Anterior

13 (6.1)

4 (7.8)

9 (5.6)

0.087*

 Intermediate

18 (8.5)

4 (7.8)

14 (8.7)

 Posterior

163 (76.9)

34 (66.7)

129 (80.1)

 Panuveitis

18 (8.5)

9 (17.6)

9 (5.6)

Anterior segment findings, n (%)

 Anterior chamber cells

96 (44.9)

29 (54.7)

61 (41.2)

0.083*

 Keratic precipitates

42 (19.6)

12 (22.6)

30 (18.6)

0.703*

 Posterior synechiae

24 (11.2)

4 (7.5)

20 (12.4)

0.488*

 Cataract

16 (7.5)

6 (11.3)

10 (6.2)

0.551*

 Conjunctival hyperemia

8 (3.7)

3 (5.7)

5 (3.1)

0.806*

 Keratitis

4 (1.9)

1 (1.9)

3 (1.9)

 > 0.999†

 Nodular scleritis

3 (1.4)

3 (5.7)

0 (0.0)

0.015†

Posterior segment findings, n (%) [n = 212 eyes: 51 eyes of women, 161 eyes of men]§

 Vitritis

94 (44.3)

15 (28.8)

79 (49.4)

0.019*

 Papillitis

68 (32.1)

15 (28.8)

53 (33.1)

0.684*

 Retinal vasculitis

58 (27.4)

11 (21.2)

47 (29.4)

0.547*

 Retinitis

54 (25.5)

13 (25.0)

41 (25.6)

0.796*

 Choroiditis/chorioretinitis

30 (14.2)

8 (15.4)

22 (13.8)

0.624*

 Cystoid macular oedema

11 (5.2)

3 (5.8)

8 (5.0)

0.678*

 Exudative retinal detachment

9 (4.2)

2 (3.8)

7 (4.4)

0.752*

 Epiretinal membrane

6 (2.8)

0 (0.0)

6 (3.8)

0.340†

 Rhegmatogenous retinal detachment

3 (1.4)

0 (0.0)

3 (1.9)

0.999†

 Choroidal neovascularization

2 (0.9)

2 (3.8)

0 (0.0)

0.059†

 Neuroretinitis

1 (0.5)

0 (0.0)

1 (0.6)

 > 0.999†

  1. n = 214 eyes, 53 eyes of women and 161 eyes of men, unless otherwise stated.
  2. *Generalized estimating equation models.
  3. Fisher’s exact test.
  4. Two eyes with isolated scleritis were excluded from the classification.
  5. §Evaluation of posterior segment was not possible in 2 eyes (0.9%) of 2 patients due to media opacities.