Table 3 Ocular complications and loss of best-corrected visual acuity for eyes of patients with ocular syphilis.

From: Influence of gender on clinical presentation, management practices and outcomes of ocular syphilis

Complication

All (n = 204)

Women (n = 50)

Men (n = 154)

Number at risk

Number of events

Incidence rate (per eye-year)

Poisson Exact CI 95%

Number at risk

Number of events

Incidence rate (per eye-year)

Poisson Exact CI 95%

Number at risk

Number of events

Incidence rate (per eye-year)

Poisson Exact CI 95%

Cataract

185

16

0.18

0.10–0.28

42

3

0.16

0.03–0.37

143

13

0.2

0.11–0.34

Epiretinal membrane

200

11

0.09

.04–0.16

50

2

0.06

0.01–0.21

150

9

0.11

0.05–0.21

Glaucoma/ocular hypertension

202

11

0.10

0.05–0.17

50

1

0.03

0.001–0.16

152

9

0.11

0.05–0.22

Optic nerve atrophy

204

9

0.07

0.03–0.14

50

2

0.06

0.01–0.21

154

7

0.08

0.03–0.17

Rhegmatogenous retinal detachment

204

6

0.05

0.02–0.11

50

0

0

NA

154

6

0.07

0.03–0.15

Cystoid macular edema

191

0

0

NA

47

0

0

NA

144

0

0

NA

Choroidal neovascularization

200

0

0

NA

48

0

0

NA

152

0

0

NA

Retinal vascular occlusionb

202

0

0

NA

50

0

0

NA

152

0

0

NA

Visual acuity

 ≤ 20/50

69

4

0.10

0.03–0.25

10

0

0

NA

59

4

0.11

0.03–0.29

 ≤ 20/200

126

5

0.06

0.02–0.14

33

2

0.08

0.01–0.03

93

3

0.05

0.01–0.15

  1. n = 204 eyes, 50 eyes of women and 154 eyes of men.
  2. NA not applicable.
  3. *One patient had retinal vascular occlusion secondary to diabetic retinopathy that is not included here.
  4. Ocular hypertension was recorded when IOP exceeded 21 mmHg by Goldmann applanation tonometry. Glaucoma was diagnosed when the raised IOP was associated with characteristic glaucomatous field defects and/or retinal nerve fibre layer thinning.