Table 1 Participant characteristics and their relation with serum neurofilament light chain.

From: The limited role of serum neurofilament light chain in predicting pain severity of patients with diabetic polyneuropathy

Characteristics

Description Mean ± SD

Relation (NfL) r

N

Age

61.49 ± 11.10

0.1929

42

Sex, female (n, %)

10, 24%

 

42

Body weight

70.25 ± 13.78

 − 0.1164

42

 Male

70.21 ± 15.16

 

32

 Female

70.40 ± 9.77

 

10

Type of diabetes (n)

 Type 1, type 2

0, 42

  

Current smoker

31%

 

42

Current alcohol intake

38%

 

42

Weekly exercise (minutes, %)

415.28 ± 535.79, 43%

 − 0.1523

18

Abnormality of neurophysiology (NCS, SSR, NCS and SSR, %)

14, 3, 16, 79%

 

33

NfL (pg/mL)

24.84 ± 12.63

 

42

Duration of painful neuropathy (months)

56.93 ± 72.85

 − 0.07814

42

PainDETECT, seven items

14.14 ± 6.35

0.07814

42

 Burning

2.17 ± 1.67

 − 0.2215

42

 Tingling

3.02 ± 1.68

 − 0.03366

42

 Pain by light tough

1.17 ± 1.43

0.02784

42

 Electric shock-like pain

1.79 ± 1.70

0.2867

42

 Pain on cold/heat stimulation

1.43 ± 1.33

0.04111

42

 Numbness

2.52 ± 1.67

0.2407

42

 Pain by slight pressure

2.05 ± 1.82

 − 0.03479

42

BPI—severity

4.05 ± 2.08

0.04345

42

BPI—interference

3.68 ± 2.73

 − 0.001165

42

Diabetes duration (years)

14.13 ± 10.3

0.2621

42

HbA1c

8.19 ± 2.01

0.4284*

35

LDL-C

83.58 ± 29.55

 − 0.1517

36

C-peptide

2.31 ± 2.01

 − 0.03799

26

GFR (mL/min/1.73 m2)

84.48 ± 30.66

 − 0.3644*

34

Creatinine

1.05 ± 0.82

0.4042*

34

Fasting glucose

137.96 ± 41.53

0.2395

25

  1. BPI, Brief pain inventory; GFR, glomerular filtration rate; LDL-C, low-density lipoprotein cholesterol; NCS, nerve conduction study; NfL, neurofilament light chain; SSR, sympathetic skin response (*p < 0.05, **p < 0.01).
Back to article page