Figure 3
KPNA2 regulated gene expression in AGS cells. (A) KPNA2 expression was quantified by RT‒qPCR. Error bars represent the mean ± SEM. (B) PCA of two groups of samples based on the normalized gene expression level. (C) Identification of KPNA2-regulated genes. (D) Hierarchical clustering of DEGs in control and KPNA2-knockdown samples. (E,F) The top ten representative GO biological processes of up- or downregulated genes. (G) RNA-seq and RT‒qPCR demonstrated that some differentially expressed genes were regulated by KPNA2. The error bars indicate the means ± SEMs. ***p < 0.001.
