Table 4 HR (for a 1-SD increase) and Harrell’s C-index of the standard and outcome-specific HLIs for all-cause mortality, T2D, CVD and cancer.

From: On the use of the healthy lifestyle index to investigate specific disease outcomes

Event

HRa (1-SD increase)

Harrell’s C-indexb

Standard HLI

Outcome-specific HLI

Standard HLI

Outcome-specific HLI

Simplified HLI (based on binary scores)

 Death

0.76 (0.75, 0.77)

0.71 (0.70, 0.72)

0.60 (0.60, 0.61)

0.62 (0.62, 0.63)

 T2D

0.71 (0.70, 0.72)

0.60 (0.59, 0.61)

0.61 (0.60, 0.62)

0.67 (0.66, 0.68)

 CVD

0.82 (0.80, 0.83)

0.74 (0.73, 0.75)

0.59 (0.58, 0.60)

0.61 (0.60, 0.62)

 Cancer

0.89 (0.88, 0.90)

0.87 (0.86, 0.88)

0.54 (0.54, 0.55)

0.55 (0.54, 0.55)

HLI (based on categorical scores)

 Death

0.73 (0.72, 0.74)

0.68 (0.68, 0.69)

0.61 (0.61, 0.62)

0.64 (0.63, 0.64)

 T2D

0.66 (0.64, 0.67)

0.43 (0.42, 0.44)

0.63 (0.62, 0.64)

0.72 (0.72, 0.73)

 CVD

0.77 (0.75, 0.78)

0.70 (0.69, 0.72)

0.60 (0.59, 0.61)

0.62 (0.61, 0.63)

 Cancer

0.88 (0.87, 0.89)

0.85 (0.84, 0.86)

0.55 (0.54, 0.55)

0.55 (0.55, 0.56)

  1. aCox models used age as the main time scale, were stratified on study center, sex, and age at recruitment, and were adjusted for education level, height, and energy intake from non-alcoholic sources, and, for women, menopausal status and use of postmenopausal hormones.