Figure 1 | Scientific Reports

Figure 1

From: Taurine, alpha lipoic acid and vitamin B6 ameliorate the reduced developmental competence of immature mouse oocytes exposed to methylglyoxal

Figure 1

MGO diminishes the developmental competence of COCs. COCs were cultured in IVM medium with indicated concentrations of MGO (20, 40, 75 and 150 µM) for 16–18 h and then IVF was carried out on matured COCs and then cultured in G-TL medium for 4.5 days; (A) Maturation rate/ GV, (B) 2PN formation rate/ GV and (C) Blastocyst rate/ GV; At least 50 COCs were cultured in each replicate of each treatment group. Five replicates were included. Data are presented as means ± SEM. Different letters (a, b, and c) indicate significant differences between the treatment groups at P < 0.05. Statistical differences between groups were assessed using one-way ANOVA with LSD post-hoc test.

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