Figure 3 | Scientific Reports

Figure 3

From: Fibroblast growth factor 23 inhibition attenuates steroid-induced osteonecrosis of the femoral head through pyroptosis

Figure 3

FGF23 promotes the secretion of inflammatory factors that damage blood vessels. (A) Circulating FGF23 expression. (B) Serum phosphate level. (C) Immunohistochemical staining of VEGF and CD31-related antigens and vascular density in the femoral head. (D) VEGF-A isoform expression in serum. (E–G) Levels of inflammatory factors including IL-1β, IL-6, TNF-α in serum of SONFH. (H) Western blot to detect the expression levels of proteins related to pyroptosis signaling pathway. *P < 0.05 versus NC group. #P < 0.05 versus LacZ group.

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