Figure 5 | Scientific Reports

Figure 5

From: Fibroblast growth factor 23 inhibition attenuates steroid-induced osteonecrosis of the femoral head through pyroptosis

Figure 5

FGF23 silencing promotes angiogenesis in vitro. (A) The expression level of FGF23 and HIF-1α in HUVECs after hypoxia was detected by western blot. (B)Tube-forming assay in vitro to detect the effect of FGF23 on the formation of official lumen-like structures in HUVECs. (C) Effect of FGF23 on VEGF, an angiogenesis-related protein in HUVECs. (D) Immunofluorescence staining images of HUVECs after interference with FGF23. (E) Gamma-H2aX staining was used to detect DNA damage induced by FGF23 in HUVEC. *P < 0.05 versus NC group. #P < 0.05 versus LacZ group.

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