Table 1 Cell death status definitions.

From: Exploring cell death mechanisms in spheroid cultures using a novel application of the RIP3-caspase3-assay

 

RIP3-status

Caspase3-status

RIP1-dependent Apoptosis

Positive

Positive

Apoptosis

Negative

Positive

Necroptosis

Positive

Negative

Other cell death

Negative

Negative

  1. Caspase3-positive signal indicating an apoptotic cell, RIP3-positive signal indicating a necroptotic cell, caspase3- and RIP3-positive signal indicating a RIP1-dependent apoptosis and no caspase3- or RIP3-signal indicating other forms of cell death.
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