Figure 6
From: Genomic surveillance of malaria parasites in an indigenous community in the Peruvian Amazon
Population genetic analysis and connectivity of Pf samples from NJ (n = 58) and other remotes areas: Mazan (n = 9), Santa Emilia (n = 12), Andoas (n = 4). (a) PCA of Pf samples, showing some clusters with samples from different areas. The shape/color schemes represent to each of area/time of collection. PCA. (b) Expected heterozygosity (He). Each dot represents the mean He of 17/28 non-fixed positions from the SNP barcode for all samples in each group. Low to moderate diversity was noted. (c) Pairwise Fst statistic among the groups. The heatmap color scheme was based on the maximum and minimum of Fst values (numbers at the center of each square). Mazan samples were the most differentiated. (d) Network inferred by IBD between Pf isolates. Edges connecting parasite pairs indicate that > 45% of their genomes descended from a common ancestor. Node colors indicate the 5 groups. Clustering pattern was similar to PCA.
