Figure 4

ROC and stratification graphs for combined (common + specific) genes in females. (A) AUROC curve for the risk score using the four combined female genes. (B) Box plot showing the disease risk score cut-off between active TB and OD groups. The dotted line indicates the risk score cut-off estimated using the Youden index. SN = sensitivity, SP = specificity, AT = active tuberculosis, OD = other disease. (C) Box plots of the four combined female genes selected for risk score construction. Log normalized values obtained from microarray are represented as expression values for each gene. p-values are indicated above the graphs (Unpaired t-test).