Figure 7 | Scientific Reports

Figure 7

From: Exploration of effective biomarkers for venous thrombosis embolism in Behçet’s disease based on comprehensive bioinformatics analysis

Figure 7

Evaluation of ROC and nomogram construction. (A) Differential expression is observed in four genes when comparing the VTE and control groups (****, p < 0.0001). (B) The ROC curve was utilized to evaluate the diagnostic efficacy of the four hub genes (E2F1, GATA3, HDAC5, and MSH2) in identifying VTE in patients with BD, demonstrating satisfactory diagnostic performance with AUC and 95% CI displayed in each panel. (C) The construction of a diagnostic nomogram employing the four genes aims to enhance the diagnosis of VTE in patients with BD. (D) The ROC curve for the nomogram is depicted in patients with BD presenting VTE. (E) Differential expression is observed in four genes via qRT-PCR when comparing the BD with VTE group and BD without VTE group (*, p < 0.05; ***, p < 0.001).

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