Table 1 Patient characteristics at the index stroke.
Overall | Subject with MRI at 7 years | Subjects without MRI at 7 years | |
|---|---|---|---|
(n = 316) | (n = 187) | (n = 129) | |
Age in years, mean (SD) | 53 (11) | 53 (11) | 54 (12) |
Male sex, no. (%) | 204 (65) | 122 (65) | 82 (64) |
Hypertension, no. (%) | 171 (54) | 102 (55) | 69 (53) |
Diabetes mellitus, no. (%) | 54 (17) | 27 (14) | 27 (21) |
Hyperlipidemia, no. (%) | 215 (68) | 129 (69) | 86 (67) |
Smoking, no. (%) | 123 (39) | 66 (35) | 57 (44) |
Subtype—Cryptogenic, no. (%) | 110 (35) | 71 (38) | 39 (30) |
- Small artery occlusion, no. (%) | 55 (17) | 36 (19) | 19 (15) |
- Large artery atherosclerosis, no. (%) | 46 (15) | 22 (12) | 24 (19) |
- Cardioembolic, no. (%) | 38 (12) | 16 (9) | 22 (17)* |
- Cervical artery dissection, no. (%) | 29 (9) | 19 (10) | 10 (8) |
- Other determined, no. (%) | 13 (4) | 7 (4) | 6 (5) |
-Undetermined, no. (%) | 25 (8) | 16 (9) | 9 (7) |
SSS, M (IQR) | 54 (43 to 56) | 54 (46 to 57) | 51 (32 to 55)** |
NIHSS (estimated), M (IQR) | 2 (1 to 6) | 2 (1 to 5) | 3 (2 to 11)** |
Infarct location—Supratentorial cortical, no. (%) | 129 (41) | 70 (37) | 59 (46) |
- Supratentorial non cortical, no. (%) | 87 (28) | 51 (27) | 36 (28) |
- Infratentorial, no. (%) | 46 (15) | 32 (17) | 14 (11) |
- Supra and infratentorial, no. (%) | 28 (9) | 21 (11) | 7 (5) |
- Undetermined, no. (%) | 26 (8) | 13 (7) | 13 (10) |
Small infarcts (< 2.5 cm3), no. (%) | 144 (46) | 98 (52) | 46 (36) |
Fazekas—Deep WMHs > 1, no. (%) | 57 (18) | 30 (16) | 27 (21) |
- Periventricular WMHs > 1, no. (%) | 38 (12) | 22 (12) | 16 (12) |
Infarct vol. [cm3], mean (SD) | 27.9 (54.5) | 20.7 (45.3) | 38.4 (64.4)** |
WMH vol. [cm3], mean (SD) | 2.9 (6.5) | 2.6 (6.3) | 3.4 (6.8)* |
Serum NfL [pg/ml], mean (SD) | 177 (325) | 135 (229) | 240 (423)* |
