Table 4 Diagnostic performance of potential dichotomous tests based on meeting the cut-off criteria determined on ROC curves.

From: Evaluating the predictive efficacy of first trimester biochemical markers (PAPP-A, fβ-hCG) in forecasting preterm delivery incidences

Parameter

OR

95% CI

Sensitivity (95%CI)

Specificity

PPV

NPV

Accuracy

PTB < 35 weeks of gestation

       

  PAPP-A MoM < 1.18

4.27

1.48–12.34

86.67%

39.70%

3.65%

99.12%

40.90°%

PTB < 37 weeks of gestation

       

  PAPP-A < 3.39

2.8

1.74–4.49

65.85%

59.22%

10.90%

95.82%

59.69%

  PAPP-A MoM < 0.71

3.11

1.97–4.92

46.34%

78.30%

13.92%

95.07%

76.05%

  Free bHCG < 41.16

2.57

1.55–4.26

73.17%

50.00%

9.98%

96.10%

40.31%

  Free bHCG MoM < 1.31

2.12

1.24–3.64

78.05%

37.45%

8.63%

95.75%

40.31%

pPROM

       

  bHCG < 40.06

3.69

1.87–7.26

78.85%

49.77%

6.83%

98.05%

51.07%

  bHCG MoM < 1.3

2.58

1.28–5.20

80.77%

38.10%

5.74%

97.70%

40.01%

  PAPP-A < 3.96

2.409

1.30–4.44

71.15%

49.41%

6.16%

97.35%

50.38%

  PAPP-A MoM < 0.67

2.76

1.55–4.9

40.38%

80.33%

8.75%

96.65%

78.55%

Spontaneus preterm labour

       

 PTB < 37 weeks of gestation

       

  Free bHCG < 26.65

8.0364

4.36–14.81

27.80%

75.60%

5.40%

95.40%

24.40%

  bHCG MoM < 1.302

2.1611

1.12–4.15

79.60%

38.20%

6.10%

97.40%

40.20%

  PAPP-A < 3.38

1.968

1.13–3.42

59.30%

59.20%

6.80%

96.70%

59.20%

  PAPP-A MoM < 0.688

2.6567

1.51–4.66

38.90%

81.10%

9.40%

96.40%

79.10%

  1. OR—odds ratio, CI—confidence index, PPV—positive predictive value, NPV—negative predictive value.