Figure 3 | Scientific Reports

Figure 3

From: Brain activity changes after high/low frequency stimulation in a nonhuman primate model of central post-stroke pain

Figure 3

Somatosensory activity changes associated with rTMS. (A–D) Brain activity associated with cutaneous tactile stimulation to the right hand compared with that to the left hand in the pre-lesion condition (A), post-lesion condition (before rTMS) (B), after Lf-rTMS (C), and after Hf-rTMS (D). Statistical significance was set at p < 0.05 FWE cluster correction (primary clustering threshold p < 0.001, uncorrected). The statistical t-maps were superimposed on the macaque template52, and the t-values are presented on a color scale. ACC, anterior cingulate cortex; Am, amygdala; CD, caudate nucleus; MCC, midcingulate cortex; M1, primary motor cortex; PGa, anterior subdivisions of the angular gyrus; PIC, posterior insular cortex; PPC, posterior parietal cortex; S1, primary somatosensory cortex; S2, secondary somatosensory cortex; Th, thalamus; TPO, temporoparietooccipital junction; rTMS, repetitive transcranial magnetic stimulation; Lf, low frequency; Hf, high frequency; FWE, family-wise error.

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