Table 2 Characteristics of PNS patients and clinical impact of using old ALB-I cut-offs.

From: The different serum albumin assays influence the prescriptions in children with primary nephrotic syndrome

 

BCG group

IN group

P values

N

N (%) or Median (IQR)

N

N (%) or Median (IQR)

Age (years)

216

5.84 (6.38)

206

4.10 (5.00)

0.06

Male

216

154 (71.30%)

206

157 (76.21%)

0.27

Weight (kg)

216

20.25 (19.00)

206

17.50 (14.00)

0.02

Hospitalization duration (days)

216

11 (7)

206

10 (7)

0.07

UV/weight (ml/kg)

216

45.04 (33.39)

206

48.86 (30.39)

0.18

Urinary Protein ≥ 3 + 

211

146(69.19%)

204

132(64.71%)

0.33

Cr (umol/L)

216

28(16)

206

25(12)

 < 0.01

CysC (mg/L)

216

0.81(0.28)

206

0.87(0.21)

 < 0.01

urea (mmol/L)

215

4(2.36)

206

4.16(2.11)

0.45

TC (mmol/L)

194

10.06(4.04)

194

10.37(4.97)

0.88

TG (mmol/L)

193

2.48(1.85)

193

2.59(1.77)

0.93

Using Diuretics

216

(75.46%)

206

145(70.39%)

0.24

ALB (g/L)a

216

17.80 (10.80)

206

12.20 (11.70)

 < 0.01

Hypoproteinemiab

216

178 (82.40%)

206

176 (85.40%)

0.43

Severe hypoproteinemia

ALB-I < 20 g/Lc

216

131 (60.60%)

206

155 (75.20%)

 < 0.01

ALB-I < 15 g/Ld

216

206

129 (62.60%)

0.69e

Cases using human albumin injections

216

65 (30.09%)

206

83 (40.29%)

0.03

ACAI/weight (g/kg) used

216

0 (0.44)

206

0 (1.07)

0.01

AEAI/weight (CNY/kg) used

216

0 (17.38)

206

0 (42.39)

0.01

  1. UV urine volume, Cr creatinine, CysC Cystatin C, TC total cholesterol, TG triglyceride, ACAI/weight average consumption of albumin injections per case/weight during hospitalization, AEAI/weight average expenditure of albumin injections per case/weight during hospitalization.
  2. aTake the earliest albumin measurement of the patient during each hospitalization.
  3. bUse a threshold of 30 g/L for hypoalbuminemia.
  4. cUse a threshold of 20 g/L for severe hypoalbuminemia in the IN group.
  5. dUse a threshold of 15 g/L for severe hypoalbuminemia in the IN group.
  6. e60.60% VS. 62.60%