Table 1 Immune cell infiltration of circadian genes.
From: Exploring transcriptomic databases: unraveling circadian gene disruptions in lower grade glioma
Gene | B cell_EPIC | T cell CD4 + _EPIC | T cell CD8 + _EPIC | ||||||
|---|---|---|---|---|---|---|---|---|---|
Correlation | P value | Adjusted P value | Correlation | P value | Adjusted P value | Correlation | P value | Adjusted P value | |
ARNTL | 0.240 | 0.000 | 0.000 | 0.248 | 0.000 | 0.000 | 0.282 | 0.000 | 0.000 |
ARNTL2 | 0.307 | 0.000 | 0.000 | 0.350 | 0.000 | 0.000 | 0.441 | 0.000 | 0.000 |
CLOCK | 0.476 | 0.000 | 0.000 | 0.455 | 0.000 | 0.000 | 0.462 | 0.000 | 0.000 |
CRY1 | 0.121 | 0.008 | 0.034 | 0.131 | 0.004 | 0.016 | 0.157 | 0.001 | 0.004 |
CRY2 | 0.603 | 0.000 | 0.000 | 0.554 | 0.000 | 0.000 | 0.484 | 0.000 | 0.000 |
NPAS2 | 0.326 | 0.000 | 0.000 | 0.376 | 0.000 | 0.000 | 0.416 | 0.000 | 0.000 |
NR1D1 | 0.382 | 0.000 | 0.000 | 0.330 | 0.000 | 0.000 | 0.282 | 0.000 | 0.000 |
NR1D2 | 0.570 | 0.000 | 0.000 | 0.509 | 0.000 | 0.000 | 0.492 | 0.000 | 0.000 |
PER1 | − 0.153 | 0.001 | 0.010 | − 0.169 | 0.000 | 0.002 | − 0.115 | 0.012 | 0.074 |
PER2 | 0.411 | 0.000 | 0.000 | 0.398 | 0.000 | 0.000 | 0.388 | 0.000 | 0.000 |
PER3 | 0.244 | 0.000 | 0.000 | 0.116 | 0.011 | 0.036 | 0.107 | 0.019 | 0.085 |
RORA | 0.402 | 0.000 | 0.000 | 0.326 | 0.000 | 0.000 | 0.357 | 0.000 | 0.000 |
RORB | 0.485 | 0.000 | 0.000 | 0.456 | 0.000 | 0.000 | 0.493 | 0.000 | 0.000 |
RORC | 0.121 | 0.008 | 0.045 | 0.108 | 0.018 | 0.066 | 0.219 | 0.000 | 0.000 |
Gene | Myeloid dendritic cell_QUANTISEQ | Macrophage_EPIC | Neutrophil_CIBERSORT | ||||||
|---|---|---|---|---|---|---|---|---|---|
Correlation | P value | Adjusted P value | Correlation | P value | Adjusted P value | Correlation | P value | Adjusted P value | |
ARNTL | 0.149 | 0.001 | 0.007 | − 0.182 | 0.000 | 0.000 | 0.035 | 0.448 | 0.572 |
ARNTL2 | 0.347 | 0.000 | 0.000 | − 0.114 | 0.013 | 0.028 | 0.071 | 0.119 | 0.179 |
CLOCK | 0.165 | 0.000 | 0.002 | − 0.143 | 0.002 | 0.006 | 0.127 | 0.006 | 0.011 |
CRY1 | 0.239 | 0.000 | 0.000 | − 0.070 | 0.124 | 0.222 | 0.062 | 0.173 | 0.277 |
CRY2 | − 0.063 | 0.171 | 0.329 | − 0.506 | 0.000 | 0.000 | − 0.132 | 0.004 | 0.013 |
NPAS2 | 0.320 | 0.000 | 0.000 | − 0.231 | 0.000 | 0.000 | − 0.023 | 0.621 | 0.750 |
NR1D1 | 0.037 | 0.415 | 0.676 | − 0.297 | 0.000 | 0.000 | − 0.135 | 0.003 | 0.022 |
NR1D2 | 0.066 | 0.149 | 0.333 | − 0.317 | 0.000 | 0.000 | − 0.031 | 0.493 | 0.659 |
PER1 | − 0.199 | 0.000 | 0.000 | 0.032 | 0.486 | 0.715 | − 0.008 | 0.870 | 0.962 |
PER2 | 0.217 | 0.000 | 0.000 | − 0.266 | 0.000 | 0.000 | − 0.072 | 0.114 | 0.228 |
PER3 | − 0.153 | 0.001 | 0.005 | − 0.081 | 0.077 | 0.157 | − 0.062 | 0.174 | 0.310 |
RORA | 0.108 | 0.018 | 0.060 | − 0.255 | 0.000 | 0.000 | 0.031 | 0.502 | 0.615 |
RORB | 0.170 | 0.000 | 0.001 | − 0.364 | 0.000 | 0.000 | − 0.031 | 0.500 | 0.675 |
RORC | 0.232 | 0.000 | 0.000 | − 0.082 | 0.074 | 0.193 | 0.006 | 0.895 | 0.949 |
